Image credit: Barth van Rossum.
Our work focuses on mammalian cell engineering of next-generation molecular sensors, actuators, and genetic functions for molecular imaging and remote spatiotemporal control of cellular processes across multiple scales. We apply these biosynthetic devices to establish bidirectional communication with cellular circuits in organoids and preclinical model organisms to reverse-engineer cellular network function and aid future imaging-controlled regenerative and cell therapies.
References
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